For many years now, we have known that eating cruciferous vegetables is a good way of decreasing the chance of getting prostate cancer. So what is it about these vegetables that has
an anti-cancer effect? And how does it work? It turns out the active ingredient in cruciferous vegetables that’s responsible is something called 3,3′-diindolylmethane, or DIM for short. Previous studies have shown that DIM slows down the growth rate of prostate cancer cells and also causes them to die by stimulating apoptosis. But that’s not all!
All prostate cancers are stimulated by male hormone testosterone. That’s why one of the most popular ways to fight prostate cancer is by decreasing the testosterone effect with anti-testosterone drugs. These drugs are not needed!!! That’s because DIM does the same thing! The beauty of DIM, though, is that its ant-testosterone effect is limited to prostate cancer cells! This means no serious side effects of anti-testosterone drugs. The new study not only points out how effective DIM is at doing this, but also shows how DIM works!
After given 225 mg of DIM, twice a day, for two weeks! It shut down the androgen receptors! In fact now 96% of the prostates had a complete absence of androgen receptors. After initially 100% first tested positive for receptors. PSA levels went down in 71% of the men tested after taking the DIM for only two weeks!
Ref: Hwang,C.,S. Sethi, et. al. “Anti-androgenic activity of absorption-enhanced 3, 3′-diindolylmethane in prostectemy patients” Am j Transl Res. 2016 January 15;8(1):166-76